Colorado completed its season-opening three-game road trip at 2-1. Boston split its first two games – both at home.
Tuukka Rask made 19 saves for the Bruins.
The Avalanche grabbed a 1-0 lead when Andrighetto’s shot from the slot slipped into the net off Rask’s glove 4:41 into the opening period.
Compher completed a 2-on-1 break with former Bruin Carl Soderberg by firing a wrister over Rask’s left shoulder to make it 2-0 midway into the period with a short-handed goal. Yakupov scored when Rask came out to chase a loose puck along the boards 6:07 into the third. And Yakupov added his second goal of the game with 44 seconds left in the third.
A “Let’s Go Red Sox!” chant broke out late in the game at TD Garden – a little before the Red Sox took the lead on Andrew Benintendi’s two-run homer in the fifth inning.
Public transportation heading into Boston was filled with fans wearing both Bruins and Red Sox jerseys with the two teams starting at nearly the same time. The Red Sox played Game 4 of the ALDS against Houston about 3 miles away at Fenway Park.
The Bruins’ best chance of the first two periods came when David Pastrnak came charging in along the left wing, cut in front and attempted to tuck the puck behind Varlamov, but he held his left pad along the ice next to the right post.
NOTES: Bruins D Torey Krug and C Austin Czarnik were both removed from injured reserved before the game and played. Boston’s forwards Noel Acciari (surgery left index finger) and David Backes (diverticulitis) were both placed on IR before the game. . It was the fourth time in eight seasons that Colorado played in Boston on Columbus Day. … Bruins C Patrice Bergeron played his 900th NHL game.
The teams face each other again in Colorado on Wednesday.