After scoring 31-seconds apart in the first period, the Predators and Blackhawks exchanged goals in a 22-second span of the second period.
Jonathan Toews put the Blackhawks up 2-1 36-seconds into the second period.
Mattias Ekholm beat Scott Darling to tie the game 2-2 just moments later.
Chicago has since taken a 4-2 lead on goals from Brandon Saad and Brent Seabrook.