Wayne Simmonds’ power play goal at 5:04 of the third period gave Philadelphia a 3-1 lead Friday night.
The Flyers appeared headed for a win.
However, Jared Boll and Cam Atkinson scored to tie it 3-3 forcing overtime and Artem Anisimov netted the winner at 2:17 of the extra period.
It was the second time in as many meetings Columbus edged Philly in overtime.
The Jackets have now won three of four meetings between the two clubs.
“It’s pretty embarrassing,” said Sean Couturier per CSNPhilly.com. “We’re in the playoff hunt. You can’t have an effort like that. We’re not gonna go far if we play like that.
“If we want to, we can be one of the best teams in the league. We gotta play our game and start putting pressure and pucks on net and tight defense. The last two games have been pretty embarrassing the way we lose these games.”
It was the second time this week the Flyers have squandered a third period lead and lost in overtime.
On Tuesday night Philly was up 1-0 in the third on the Montreal Canadiens. Tomas Plekanec scored with less than eight minutes remaining and David Desharnais won it in overtime.
“There’s something wrong with losing these games the way we’re losing them,” Couturier said. “We got to fix what’s wrong and play better for 60 minutes. It’s not a 40- or 45-minute game.”
The Flyers are currently seven points back of Boston for the second wild card spot in the Eastern Conference.
Philadelphia will look to avoid a third straight loss Sunday when they visit Buffalo. The Flyers won the only other meeting between the two clubs 4-3 on Jan. 17.