Goaltender Ray Emery had a tough return from the All-Star break.
The Flyers’ starter allowed two goals on the first four shots of the game and was replaced by Steve Mason just 5:50 into the first period.
Connor Murphy opened the scoring for the Arizona Coyotes with his third of the season and Martin Erat netted his seventh in a 2:17 span.
Flyers’ coach Craig Berube had seen enough sending Mason in for Emery.
Mason is making his first appearance since Jan. 10 when he left Philadelphia’s game against Boston with a lower body injury.